Blast of Genius: There are a lot of good things you can do for six mana, and when you draw and discard and already have six mana in play, youre generally not interested in discarding the most expensive spell you have
Annihinfect (Whenever this creature attacks, defending player sacrifices a permanent for each poison counter they have.) Kozilek's first ability will resolve before Kozilek does
With each incarnation of vampires, the tribe has received new abilities and even new colors to their identity, dipping their toes into red, white, and sometimes even blue
Maybe not for artifacts, but for some card type or sub type that isn't so easy to get five out on the first turn
Its like a white Phyrexian Arena, and youll not even lose life